This daily weight loss pill could be a game changer! It’s called Orforglipron
Robert Price | Last update: 6th May 2025
Big news on the horizon: a daily weight loss pill called orforglipron has shown promising results in clinical trials. Developed by Lilly (the makers of Mounjaro), this weight loss drug helped participants lose around 8% of their body weight over 10 months.
Unlike injections, this is a once-a-day pill designed to reduce appetite and help you feel full quicker. Early trial results suggest it’s just as effective – and just as safe – as the existing injectable drugs.

Why It Matters
For many people, the idea of taking a daily weight loss pill instead of injecting is much more appealing. It’s easier to travel with, doesn’t need refrigerating, and can be taken any time of day, with or without food. Handy, right?
Professor Rachel Batterham from Lilly says most of her patients ask for tablets over injections – and this could finally be the answer. Plus, pills mean less plastic waste and fewer supply issues down the line.
What’s Next?
Lilly plans to apply for UK approval by the end of this year. If all goes well, the pill could be available privately in 2025 – and possibly through the NHS not long after.
A Few Things to Note
Side effects are similar to other GLP-1s – nausea, diarrhoea, and occasional vomiting are possible. And as always, these drugs aren’t magic. They work best when combined with changes to diet, exercise and overall lifestyle.
Final Thoughts
A daily weight loss pill could make managing weight more accessible and more flexible for a lot of people – especially those who’ve struggled with injections. We’ll be keeping a close eye on this one.
For more info have at what The Guardian and The Independent are saying.
Would you prefer a daily pill to an injection? See what the SlimrChat community are saying – or, better still, let us know – start a chat yourself.