What is Ozempic face — and can you prevent it?

Ed Milner | Last update: 21st July 2025

What is Ozempic face?

Ozempic face is the nickname for the sagging, gaunt or drawn facial appearance that some people experience after significant weight loss on GLP-1 weight loss drugs.

You might notice:

• Looser skin around the cheeks or jawline
• A more hollow or sunken appearance
• Lines or wrinkles becoming more visible

It’s not technically a side effect of Ozempic (semaglutide) or Mounjaro (tirzepatide) — but a result of fat loss, particularly in the face.

“I love the number on the scale, but I wasn’t ready for what it did to my face.” – SlimrChat user

Read more in our news post: Ozempic tongue and Ozempic face

Why does it happen?

When you lose weight quickly, your body burns fat from all over — including the face. For some people, especially over 40, the skin doesn’t bounce back as easily, and facial volume loss becomes more noticeable.

It’s more likely if:

• You’ve lost a large amount of weight
• You’re older (collagen levels naturally decline with age)
• You already had fine lines or looser skin
• Your weight loss has been fast or unbalanced (e.g. not enough protein or muscle retention)

How to reduce the effects of Ozempic face

The good news? There are things you can do to prevent or soften the impact.

1. Prioritise protein and strength training

Maintaining muscle (including facial muscle tone) is key. Protein also supports collagen and skin repair.

2. Hydrate and nourish your skin

Dry skin looks looser and older. Stay hydrated, use a quality moisturiser, and consider products with:

• Retinol or peptides (boost collagen)
• Vitamin C (brightening and skin repair)

3. Build your weight loss gradually

Slow, steady weight loss can help your skin adapt more gently.

“I slowed my loss down, upped my water and protein, and started seeing my glow come back.” – SlimrChat member

4. Facial massage or resistance

Using gua sha tools, gentle face yoga, or even smiling exercises may help keep your facial muscles active.

5. Consider cosmetic options

Dermatologists can offer non-surgical treatments that plump or lift, like:

• Dermal fillers
• Skin tightening lasers
• Microneedling with radiofrequency

Always speak to a licensed specialist if you’re exploring these options.

Should I be worried?

No. Ozempic face isn’t dangerous — just a cosmetic side effect of weight loss. Some people notice it, others don’t.

If it bothers you, know that you have options. And for many people, these changes are temporary and settle as their body adapts.

“The way I feel inside matters more than a bit of sagging skin. I’m learning to love the new me.” – SlimrChat community member

Final thoughts

Ozempic face is real — but manageable. With the right nutrition, hydration, movement and self-care, you can support your skin and feel confident through every phase of your weight loss journey.

And remember, the SlimrChat community is here to help. You’re not the only one navigating this. We’ve been there too. Why not share your experience or may be you have some tips to help people? Either way, join the conversation by clicking the ‘Start Chat’ button below.