What’s next for weight loss drugs?
Peter Paumgardhen | Last update: 9th May 2025
The next generation of weight-loss drugs is already taking shape, with pharmaceutical companies racing to deliver treatments that are even more effective, convenient, and accessible. In a recent WIRED article, the success of current GLP-1 weight loss drugs, like Wegovy (Ozempic), Mounjaro and Saxenda, has sparked a massive surge of innovation globally (Read the full article on WIRED here).

A new era of treatment
The current weight loss drugs have transformed weight management for us, but there are still challenges. Side effects, costs and availability have created barriers for many of us who want to use drugs. This has pushed companies like Viking Pharmaceuticals, Amgen and Zealand Pharma to explore new drug innovations and delivery methods. There is a concentration on development of effective pill based treatments – taking away the need for injections – and potentially lowering costs for users and increasingly accessibility.
Innovation beyond GLP-1
The pipeline is expanding beyond the current GLP-1 weight loss drugs. Zealand Pharma’s petrelintide mimics the hormone amylin, which signals fullness to the brain with fewer side effects. Eli Lilly’s investigational drug, retatrutide, targets three mechanisms simultaneously (GLP-1, GIP, and glucagon) which has been achieving unprecedented weight loss results in trials.
Why this matters
With the demand for weight loss drugs outpacing supply in many places around the world new entrants could ease shortages and provide more tailored options. Experts believe the next wave of treatments will not only improve weight loss outcomes but also address common side effects and barriers like cost and convenience.
At SlimrChat, we know how important it is to stay informed about the latest developments in weight management. What are your thoughts on these next-gen treatments? Are you excited about new options beyond GLP-1s? Join the discussion in our forums and share your perspective on the future of weight loss drugs.
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