Are weight loss drugs right for you?

Robert Price | Last update: 2nd October 2025

Benefits of weight loss drugs

Weight loss treatments aren’t a magic fix, but they can be highly effective tools when used alongside healthier eating and movement. Some of the main benefits include:

• Clinically proven results: people can lose 15% or more of their body weight over time with GLP-1 medications. Read our article on how they work and see whether Mounjaro or Wegovy are right for you.
  
• Reduced appetite and cravings: weight loss drugs target hunger hormones, which can make it easier to resist overeating, reduce food noise and make you feel fuller for longer. Stories from our community members Vivienne, Gemma and Emily show the effects of these revolutionary treatments.
  
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  Laura has lost 11 stone

  Improved health outcomes: studies show weight loss drugs can lower the risk of type 2 diabetes, improve blood pressure and reduce cholesterol levels. There’s also research showing effects on cancer.

• Better quality of life: beyond the numbers many people report higher energy, improved sleep and more confidence. Some of our community report higher libido too!
  

I’m firmly in middle age and realised I needed a long-term plan to keep the weight off. I’d seen the effects of MJ for friends and it was clear what I should do. It’s totally worked and I’ve kept the weight off since stopping the jabs by refusing to go back to old ways. Robert, SlimrChat Founder.

Risks and side effects

It won’t be a surprise to you that these prescription weight loss medications do have some downsides. Like all prescription drugs they have been tested and trialled extensively before and after they were approved by the regulatory bodies in the UK, and overseas. Here’s the key things you should think about, discuss with your doctor or healthcare provider and ask people who’ve experienced the treatments about: 

• Common side effects: the most reported side effects (in testing and on our SlimrChat forums) are nausea, constipation, diarrhoea or fatigue. These are especially highlighted when people are at the start of their treatment. Have a look at our info on common side effects and tips to overcome side effects. 
  
• Serious risks: you should be aware that there are some more serious, but not common, risks including pancreatitis. Make sure you’re aware of these risks and your own medical history.
  
• Long-term unknowns: these are relatively new drugs so the long-term impact isn’t fully understood yet. However, widespread positive research continues to be released.
  
• Cost and access: private prescriptions can be expensive so make sure you understand the full costs (the SlimrChat price tracker goes live soon) and NHS availability is currently very limited.

I can’t even contemplate greasy foods and am pretty sure that fast food habit has fast gone! Vivienne Joy, Your Jab Life contributor

Alternatives

Weight loss drugs are just one part of the wider picture. Depending on your situation, other approaches may be safer or more sustainable:

• Lifestyle changes: building consistent habits around food, movement/ exercise, sleep and reducing stress can make a major difference.
• Behavioural support: therapy, counselling or support groups can help with emotional eating or long-standing habits.
• Medical options: for some of us bariatric surgery or weight loss medications may be recommended.
• Combination approach: many people find success blending small lifestyle shifts with or without medical support. The evidence is clear that the most enduring way to use weight loss drugs is to have them as part of an overall weight loss and lifestyle plan.

Should I use weight loss drugs? Your simple checklist

Health & medical criteria

My BMI is 30 or higher, or 27+ with weight-related conditions (such as type 2 diabetes or high blood pressure).

1. I don’t have a history of pancreatitis, gallbladder disease or thyroid cancer.
2. I’m not pregnant, breastfeeding or planning pregnancy soon.
3. I have talked (or plan to talk) to my doctor or healthcare provider before starting.
   

Lifestyle & commitment

1. I’m prepared to make healthier food and movement choices alongside medication.
2. I understand the jabs are most effective when used long-term, not just as a quick fix.
3. I have support (friends, family, SlimrChat community, or coaching) to help me stay consistent.
4. I have my plan for my weight loss journey.
5. I’m comfortable with a weekly injection routine.
   

Make it your final weight loss journey and change your life. Katie Wattam, Your Jab Life

Risks & side effects

1. I’ve read about common side effects (including nausea, constipation, fatigue) and feel ready to manage them.
2. I understand there are some rare but serious risks.
3. I’m aware that research on long-term safety is still developing.
   

Cost & access

1. I’ve checked how much private prescriptions cost, and whether I can afford ongoing treatment.
2. I know that NHS access is limited and usually reserved for certain health conditions.
3. I’ve thought about what I’ll do when I stop taking the drugs when I need to maintain my new lifestyle and approach to food.

Alternatives & support

1. I’ve already tried lifestyle changes with support, but results haven’t been enough.
2. I’ve looked into other medical or behavioural options (therapy, older medicines, surgery).
   

Most importantly I’m clear on my goals. Improving my health, mobility or confidence.

SlimrChat Take Out

Weight loss drugs can be life-changing for some people but they’re not the right fit for everyone. The best next step is to speak with your doctor or healthcare provider about your health history, goals and options.

Remember: your weight loss journey is personal. Whether through medication, lifestyle changes, or a mix of both, the aim is to feel healthier, happier, and more in control. We launched SlimrChat to help people like you, and me, through this journey if you decide to start it.